The game takes place 3 years after Gods Eater Burst. A new pandemic caused by "Red Rain" has struck the Far East Branch. Members of Special Forces "Blood", an affiliate of Fenrir who reside in a mobile base, are sent to investigate. It will feature a new setting, as well as new protagonist, new monsters, and new weapons.
Yusuke Tomizawa, producer of God Eater, said "God Eater 2 was to pinpoint what users found fun about the game; we're taking it apart and reassembling it from scratch."
Source: Wikipedia, "God Eater 2", available under the CC-BY-SA License.