The Skylanders serie of games wants to refresh the Spyro franchise by introducing the concept of multiplatform toys translating directly into game characters. The Skylanders are the heroes of the fictional world of Skyland that, following a curse by the evil Kaos the skylanders are frozen and, miniaturized, exiled on the planet Earth. The player, as a portal master, can place those miniatures on the portal of power to bring them back to life in Skylands to fight Kaos nd bring back the Core of Light, that will exile evil once and for all.
At the moment the serie count three games, with a fourth in beta testing.
Skylanders: Spyro's Adventure, the first in the series.
Skylanders: Cloud Patrol, a spin off of Spyro's adventure for iPad
Skylanders: Giants a direct sequel to Spyro's Adventure featuring giant skylanders.
There is also a playable MMORPG currently available as beta on the official website called Skylanders Universe.
The interesting point is that by purchasing a single Skylander it will be available, by using the portal of power or the enclosed, unique code, in all the games in the series. Also, as all the character advancements and XPs are stored in the piece memory, you will be able to bring your favorite Skylander with you, and play with it on other consoles, even if the system is different from your own.