Aztec: The Curse in the Heart of the City of Gold is an adventure game designed for PlayStation. It was developed by Cryo Interactive and published by France Telecom Multimedia.
You start off with a character; Aztec who lives a life as a hunter. Everything is fine up until one day when he's hunting and he meets a man who dies, but moments before his death he provides advice to Aztec. Aztec is blamed for the murder of the man and must prove his innocence. His parents are taken hostage until he hands himself into authorities. At around the same time of all this occurring a new disease breaks out that has no cure, he must use this clue to help him out of what has occurred.
Source: Wikipedia, "Aztec: The Curse in the Heart of the City of Gold", available under the CC-BY-SA License.