Simple 1500 Series Vol. 52: The Pro Wrestling 2 is the sequel to Yuke's 1999 Japanese professional wrestling game Simple 1500 Series Vol. 22: The Pro Wrestling.
The Pro Wrestling 2 features two gameplay modes (Exhibition and Champion Road) and a Wrestler Edit mode. There are three match options inside of Exhibition Mode: Single Match, Battle Royal, and Death Match. The Champion Road mode is a career mode.