Harukanaru Toki no Naka de 2 takes place 100 years after the prior game, Harukanaru Toki no Naka de. Kyō, which resembles Kyoto in the Heian period, is in turmoil because of a power struggle going on between the emperor and the retired emperor, and the people of Kyō are falling into desperation, fearing the coming of the end of the world. Karin, a modern-day high school girl, is summoned to be the Ryūjin no Miko (龍神の神子 Priestess of the Dragon God) who will save Kyō. However, there is already a Ryūjin no Miko in Kyō who has been recognized by the retired emperor, and the eight men chosen as Karin's Hachiyō (八葉) do not believe that Karin is really the Miko.
Source: Wikipedia, "Harukanaru Toki no Naka de 2", available under the CC-BY-SA License.