Mitsume ga Tooru ("The Three-eyed One") is a video game for the Family Computer that was released by Natsume. It is based on the manga and anime called The Three-Eyed One. The main character is Hosuke Sharaku. There is also a Mitsume ga Tooru game for the original MSX called Mitsume ga Tooru: The Three-Eyed One Comes Here, which was released by Natsume two years before this one.
The player controls Hosuke Sharaku, a three-eyed child whose girlfriend was kidnapped by Hosuke's three-eyed nemesis. Hosuke has to rescue his girlfriend and defeat his nemesis.
Source: Wikipedia, "Mitsume ga Tooru", available under the CC-BY-SA License.