"Pokémon Puzzle League is a puzzle game for the Nintendo 64 console. It is based on Nintendo's Panel de Pon puzzle games, but with Pokémon likenesses. This game was only available in North America starting in 2000, making it the first Pokémon game produced for North America. The game was not available in Japan because it is based on the English dub of the anime; the Japanese received the game's Game Boy Color counterpart, Pokémon Puzzle Challenge. This is the third Pokémon game to be based on the Pokémon anime, the other two being Pokémon Yellow and Pokémon Snap, and it's also the first Pokémon game to feature Ash Ketchum, the anime's protagonist. The game was released on the Virtual Console on May 5, 2008, in the North America region, and on May 30, 2008, in the European region."
Source: Wikipedia, "Pokemon_Puzzle_League," available under the CC-BY-SA License.