The game is a side-scrolling arcade game featuring the X-Men. The original story takes place in Murderworld, a dangerous and deadly amusement park of terror. The X-Men, which include Colossus, Cyclops, Dazzler, Nightcrawler, Storm, and Wolverine, are pitted against their arch-enemies Arcade and Magneto. The game has over 500 action and combat screens, as well as some puzzle-solving.
Source: Wikipedia, "X-Men: Madness in Murderworld," available under the CC-BY-SA License.