Sesame Street: Elmo's A-to-Zoo Adventure

From the publisher's website:

Elmo's A-to-Zoo Adventure encourages literacy skills, including letter identification, letter sounds, and word families, through engaging and fun mini-games.

Explore exciting Zoo habitats including the Aquarium, Savanna, Jungle, Forest and the Arctic.

Easy to follow audio-visual directions that preschoolers can master on their own.

Use the second Wii Remote™ to drop-in and assist your child when needed.

Game difficulty adapts to your child's level.

Customize up to four profiles, set functions including difficulty level and game limits, and review the games and educational content your child has played on the Parent's Page.
Wii and Nintendo DS versions include Gameplay Helpers to simplify gameplay for your preschooler.

The Wii gameplay helper is a soft and fuzzy character cover with special grips that slips over the Wii Remote, minimizing unnecessary buttons and making it easier and more fun to hold.
For Nintendo DS, there is a jumbo click stylus designed for smaller hands, simplifying interaction with the touch screen.