Novelist Dale Brown created this fictional variant of the B-52 Stratofortress, a heavy strategic bomber in the United States Air Force. The Megafortress first appeared in Brown's novel Flight of the Old Dog and was expanded and upgraded in all of his later books.
The Megafortress has all the latest technology and carries all the latest weapons, including air-to-air missiles, anti-ship missiles, anti-tank guided missiles and even more fanciful weapons such as plasma-yield warheads. It uses an advanced stealth-style configuration, having a long SST nose and a V-tail.
In Flight of the Old Dog, the aircraft is designated the B-52I Megafortress. The EB-52 designation is first used in the second sequel, Sky Masters.
Source: Wikipedia, "Fictional military aircraft", available under the CC-BY-SA License.