Talbot is Marlowe's right-hand man and secondary antagonist in Uncharted 3: Drake's Deception. He is voiced by Robin Atkin Downes. He is the one who hired Charlie Cutter to provide security for the deal in the first level. He has a rivaly with Nathan Drake and, according to the developers, acts as the "anti-Drake", with similar looks and free running skills to rival Drake's own. Talbot is always by Marlowe's side, and later orders Cutter to shoot Nate and Sully. Despite his unassuming appearance, he is an extremely dangerous hand-to-hand combatant, able to use a combat knife with high proficiency as seen in his final confrontation with Drake and Sully in the collapsing city of Ubar. He also has a special weapon: a dart gun loaded with a special drug which grants him some hypnotic influence over people (he uses it to make Cutter disarm himself). Despite being treated with near indifference, he appears to care deeply for Marlowe, begging Nathan to save her from being consumed by the quicksand in Ubar, and is driven mad when Drake fails. He tries to murder Drake on top of a collapsing cliff overlooking the Iram of the pillars but is briefly distracted by Sully who shoots him in the shoulder with a Walther P99. He is then finally killed by Drake who puts several bullets into him before he can flatten Sully's skull with a rock, and plummets to his death.
Source: Wikipedia, "List of Uncharted characters", available under the CC-BY-SA License.