From the back of the game box:
Imagine for a moment that President John F. Kennedy did not die from his gunshot wounds in 1963...Now imagine you are President John F. Kennedy.
REELECT JFK places you in the Presidential hot seat during a fascinating alternate version of one of the most tumultuous periods in U.S. history. You assume the role of JFK and make decisions on the critical issues of 1964 - Civil Rights, Vietnam, and other events. You have the dual task of getting reelected in 1964 and solving the mystery of the attempt on your life.